I’ve written about getting started with YubiKey and using a YubiKey to authenticate with GitHub in the past few months. Yesterday, GitHub announced support for Universal 2nd Factor (U2F) and specifically, support for YubiKey devices. You can read GitHub’s announcement here and Yubico’s coverage.
Now, the steps I outlined to get up and running with a YubiKey and GitHub aren’t needed. With GitHub’s new U2F integration you simply set up a new device from your security settings. Instructions on how to do this are here.